RNA Details
Disease Name
myocardial infarction
Tissue
heart
RNA Symbol
Malat1
RNA ID
RNA Type
lncrna
Alteration Pattern
up regulation
Species
mus musculus
Detection Methods
NA
Target
miR-25-3p
Pathway
NA
PubMed ID
Title
M1 Bone Marrow-Derived Macrophage-Derived Extracellular Vesicles Inhibit Angiogenesis and Myocardial Regeneration Following Myocardial Infarction via the MALAT1/MicroRNA-25-3p/CDC42 Axis
Year
2021
Function
"MALAT1 sponged miR-25-3p to upregulate CDC42. miR-25-3p overexpression promoted oxygen-glucose deprivation-treated cell viability, proliferation, and angiogenesis."